Table 2.
Univariate and multivariate regression analysis of 90-day venous thromboembolism events (VTE) and composite adverse events (CAE)
| Crude Odds Ratio (95% CI) 90-d CAE |
Adjusted Odds Ratio (95% CI)* 90-d CAE |
Crude Odds Ratio (95% CI) 90-d VTE |
Adjusted Odds Ratio (95% CI)* 90- d VTE |
|
|---|---|---|---|---|
| Perioperative VTE pharmacologic prophylaxis |
0.59 (0.42-0.83) | 0.64 (0.44-0.93) | 0.58 (0.35-0.98) | 0.62 (0.36-1.06) |
| Age | 1.04 (1.03-1.06) | 1.04 (1.02-1.06) | 1.01 (0.99-1.03) | 1.01 (0.99-1.03) |
| Sex | 0.97 (0.69-1.37) | 1.03 (0.72-1.48) | 0.96 (0.58-1.61) | 0.88 (0.4-1.96) |
| Smoking | 1.10 (0.70-1.73) | 1.41 (0.86-2.32) | 0.90 (0.44-1.84) | 0.89 (0.4-1.96) |
| Previous history of VTE | 1.73 (0.83-3.61) | 1.49 (0.71-3.13) | 2.53 (0.99-6.42) | 2.32 (0.88-6.09) |
| Charlson Comorbidity Index 1 2 3+ |
1.10 (0.55-2.23) 1.59 (0.99-2.52) 1.98 (1.31-3.01) |
0.92 (0.45-1.89) 1.19 (0.72-1.97) 1.38 (0.87-2.21) |
0.84 (0.29-2.45) 1.41 (0.73-2.71) 1.33 (0.71-2.49) |
0.85 (0.29-2.5) 1.65 (0.84-3.25) 1.36 (0.68-2.71) |
| Pneumatic compression | 0.79 (0.43-1.44) | 0.82 (0.43-1.57) | 0.57 (0.26-1.27) | 0.54 (0.24-1.2) |
| Method of operation (open)† | 1.96 (1.23-3.11) | 1.52 (0.94-2.48) | 1.87 (0.94-3.7) | 1.57 (0.77-3.21) |
| Type of operationa‡ Left hemicolectomy Low anterior resection Abdominal perineal resection Total abdominal colectomy Colostomy takedown Perineal proctectomy |
0.82 (0.5-1.34) 0.63 (0.41-0.97) 0.78 (0.35-1.74) 1.2 (0.63-2.29) 0.82 (0.11-6.09) 1.05 (0.14-7.94) |
0.81 (0.48-1.38) 0.83 (0.52-1.3) 0.82 (0.37-1.83) 2.45 (1.25-4.82) 1.34 (0.15-12.05) 1.31 (0.17-10.18) |
1.37 (0.65-2.91) 1.21 (0.62-2.35) 0.37 (0.05-2.8) 2.69 (1.14-6.36) 2.78 (0.36-21.62) - |
1.3 (0.63-2.69) 1.42 (0.72-2.83) 0.35 (0.05-2.65) 3.84 (1.63-9.07) 4.43 (0.48-41.27) - |
| Year of operation 2006 2007 2008 2009 |
0.44 (0.21-0.88) 0.54 (0.28-1.05) 0.34 (0.18-0.67) 0.19 (0.07-0.48) |
0.39 (0.19-0.81) 0.49 (0.25-0.96) 0.36 (0.18-0.71) 0.20 (0.075-0.53) |
0.73 (0.24-2.25) 0.61 (0.21-1.84) 0.55 (0.19-1.61) 0.17 (0.03-0.92) |
0.63 (0.19-2.10) 0.68 (0.22-2.14) 0.63 (0.21-1.89) 0.17 (0.03-1.03) |
*
Adjusted for all other variables listed.
†
Compared to laparoscopic procedures.
‡
Compared to right hemicolectomies.
CAE, composite adverse event; VTE, venous thromboembolism.