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Aptamers that have entered clinical investigation in cardiovascular diseases.
| Aptamer | Target | Company | Development Stage |
|---|---|---|---|
| ARC1779 | vWF | Archemix | Phase I, II |
| ARC1172 | vWF | Archemix | Phase I |
| ARC183 | Thrombin | Archemix | Phase I |
| NU172 | Thrombin | ARCA Biopharma, Inc. | Phase I, II |
| REG1 (RB006/RB007) | Factor IXa | Regado Biosciences | Phase I, IIa, IIb |
