Table 1.

A tabulated summary of aptamer-based molecular imaging.

Target	Image tag	Imaging technique	In vivo study?	Ref.
Integrin αvβ3	Cy5	Fluorescence	No	[21]
Angiogenin	Cy5	Fluorescence	No	[24]
PSMA	Cy5, quantum dot	Fluorescence	No	[27,30,33]
Nucleolin	Cy3, quantum dot	Fluorescence	No	[36,39,40]
MUC1	Quantum dot	Fluorescence	Yes	[43]
Hepatoma cells	Quantum dot	Fluorescence	No	[44]
Hemagglutinin	Quantum dot	Fluorescence	No	[45]
Cells	Magnetic and fluorescent NPs	Fluorescence	No	[47]
Guanosine triphosphate	Tetramethylrhodamine	Fluorescence	No	[48]
Ramos cells	Cy5	Fluorescence	Yes	[50]
MRCK	Fluorophore-quencher pair	Fluorescence	No	[58]
Cancer cells	Fluorophore-quencher pair	Fluorescence	Yes	[59]
Adenosine	Gadolinium, iron oxide NPs	MRI	No	[63,64]
Thrombin	Iron oxide NPs	MRI	No	[66]
MSC	SPIO	MRI	Yes	[69]
PSMA	SPIO	MRI	No	[70]
PSMA	SPIO	MRI	Yes	[71]
Leukemia cells	Nanobubbles	Ultrasound	No	[75]
Elastase	99mTc	SPECT	Yes	[81]
Tenascin-C	Rhodamine red/99mTc/111In	Fluorescence/SPECT	Yes	[86]
MUC1	99mTc	Autoradiography	Yes	[87]
Prion protein	Silver NPs	Dark-field light scattering	No	[96]
Adenosine	Gold NPs	SERS	No	[97]
PSMA	Gold NPs	CT	No	[105]
Nucleolin	Cobalt-ferrite NPs/rhodamine/67Ga	MRI/fluorescence/SPECT	Yes	[113]