. Author manuscript; available in PMC: 2012 Oct 28.

Published in final edited form as: J Neuroimmunol. 2011 Sep 10;239(1-2):98–100. doi: 10.1016/j.jneuroim.2011.08.018

Table 1.

Expression of MBL, functional MBL and MASP-2 in plasma and CSF.

Compartment	Variable	MS group (median)	No MS group (median)	Ratio of means, MS vs. No MS (and 95% CI)	p-value
Plasma (N-49)	MBL (ng/ml)	264.7	255.4	0.84 (0.28, 2.55)	0.89
	Functional MBL (U/ml)^*	359.4	152.7	2.04 (1.00, 4.16)	0.029
	MASP-2 (ng/ml)	418.4	252.5	1.75 (1.19, 2.57)	0.004
CSF (N=27)	MBL (ng/ml)	4.18	1.76	NA^**	0.48
	Functional MBL (U/ml)	11.2	11.8	1.00 (0.70, 1.43)	0.99
	MASP-2 (ng/ml)	33.9	33.1	1.03 (0.94, 1.13)	0.51

Functional MBL shows quantitation measurement of the active MBL in the plasma through the measurement of the ability of MBL/MASP-2 complex to initiate C4 cleavage when it is bound to mannan.

^**

For MBL, 23 of the 27 subjects (85%) had levels below the limit of detection (1.64); therefore, the ratio of means could not be computed.