Table IV.
Bone marrow B cells over-expressing Bright preferentially develop into MZ cellsa.
| FO | MZ | Ratio | |
|---|---|---|---|
| CD45.2+ B cells splenic B cells (×106) | |||
| 0% BrTg (100% Control) | 35.40±8.70b | 5.66±0.94 | 6.18 |
| 50% BrTg (50% Control) | 39.23±1.62 | 8.47±0.27 | 4.63 |
| 75% BrTg (25% Control) | 27.77±2.23 | 6.99±0.82 | 4.01 |
| 100% BrTg (0% Control) | 22.90±3.46 | 10.65±1.14 | 2.14 |
Recipient mice (n = 3 per group) were analyzed after 5 weeks.
Total cell numbers (MEAN±SEM) per spleen were determined by multiplying the frequency of live cells gated as in Figure by the number of total cells per spleen and are shown ×106.