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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Mol Genet Metab. 2011 Jun 29;104(3):249–254. doi: 10.1016/j.ymgme.2011.06.016

Table 1.

Specific Activity of chemically modified PAL variants

Specific activity(IU/mg)
Rt-PAL + aprotinin 0.15
Av-p.C503S/p.C565S PAL + aprotinin 0.08
20 kDa PEGylated-Av-p.C503S/p.C565S PAL 0.16
Av-p.C503S/p.C565S/p.F18A PAL+ aprotinin 0.65
5 kDa PEGylated-Av-p.C503S/p.C565S/p.F18A PAL 1.08
10 kDa PEGylated-Av-p.C503S/p.C565S/p.F18A PAL 0.55
20 kDa PEGylated-Av-p.C503S/p.C565S/p.F18A PAL 0.55
20 kDa PEGylated-Av-p.C503S/p.C565S/p.F18A PAL+ aprotinin 0.33
Hydrogel protected nanoparticles of Av- p.C503S/p.C565S/p.F18A PAL 0.76
Barium Alginate Microspheres of Av- p.C503S/p.C565S/p.F18A PAL 1.46
Amorphous Silica particles of Av- p.C503S/p.C565S/p.F18A PAL 0.34
PTD-AvPAL TM fusion Av-p.C503S/p.C565S/p.F18A PAL + aprotinin 0.79