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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Cell Signal. 2011 Aug 18;24(1):71–76. doi: 10.1016/j.cellsig.2011.07.018

Fig. 6.

Fig. 6

Targeting RIP140 or PKCε in adipocytes enhances functional adiponectin secretion to reduce gluconeogenesis in hepatocytes. (A) The effect of conditioned media from ctrl-, RIP140- or PKCε-silenced adipocytes on gluconeogenesis in HepG2 cells in the absence (control) or presence of insulin. All values represent the means ± SD., n=3; *: P < 0.05 compared to control group in Ctrl conditioned medium. (B) The effect of conditioned media on AMPK activation in HepG2 cells. The ratio of pAMPK/AMPK was quantified. (C) Anti-adiponectin antibody (anti-adipoQ) neutralized the effect of conditioned media on glucose production ability of HepG2 in the absence of insulin. *: P < 0.05 compared to IgG group in conditioned medium from indicated silencing group.