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. Author manuscript; available in PMC: 2012 Nov 15.
Published in final edited form as: Bioorg Med Chem. 2011 Jun 12;19(22):6675–6701. doi: 10.1016/j.bmc.2011.06.011

Table 6.

Marine natural product structural revisions of absolute configuration (2005–2010).a

Proposed Structure Initial Structure Determination Method Revised Structure Structure Revision Method
graphic file with name nihms303603t89.jpg
Amphilactene derivative50(1999)
Sponge		 Mosher’s graphic file with name nihms303603t90.jpg Mosher’s51
graphic file with name nihms303603t91.jpg
Amphilactene derivative50(1999)
Sponge		 Comparison graphic file with name nihms303603t92.jpg X-ray51
graphic file with name nihms303603t93.jpg
Fusapyrone128 (1994)
Fungus		 1D & 2D NMR graphic file with name nihms303603t94.jpg HMBC NMR Comparison129
graphic file with name nihms303603t95.jpg
Deoxyfusapyrone128 (1994)
Fungus		 1D & 2D NMR graphic file with name nihms303603t96.jpg HMBC NMR Comparison129
graphic file with name nihms303603t97.jpg
Plakolide A182(2004)
Sponge		 CD graphic file with name nihms303603t98.jpg Total Synthesis183
graphic file with name nihms303603t99.jpg
4-keto-clonostachydiol184(2006)
Fungus		 Deriv. OR graphic file with name nihms303603t100.jpg Total Synthesis185
a

Theyear in which the initial structure was published is in parentheses. Only the structure determination methods used for the portion of the structure that is erroneous are mentioned in this table. Predict. = predictions based on molecular modeling. Mol. Mod. = use of geometry optimized structure. Deriv. = derivatization. Chromatog. = chiral HPLC or GC with or without derivatization.