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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Biochem Pharmacol. 2011 Aug 30;82(11):1764–1770. doi: 10.1016/j.bcp.2011.08.015

Table 1. Glucuronide product distributions relative to unreacted flavonoid.

All values are percentages of total product and unreacted flavonoid distribution. Values in parenthesis indicate products with unconfirmed structures, meaning that two alternatives are possible. A dash is used to indicate the absence of a product. All values rounded to the nearest 5%. The average standard deviation is ±5%.

Hesperetin 1A1 1A3 1A4 1A6 1A7 1A8 1A9 1A10 2B4 2B7 2B15 2B17
Hesperetin 60 15 100 10 45 70 30 75 80 60 100 100
5-O-Glucuronide - - - Trace - - - - - - - -
7-O-Glucuronide 30 10 - 90 5 10 30 15 20 30 Trace Trace
3′-O-Glucuronide 10 75 - Trace 50 20 40 10 Trace 10 Trace Trace
Naringenin 1A1 1A3 1A4 1A6 1A7 1A8 1A9 1A10 2B4 2B7 2B15 2B17
Naringenin 40 50 100 30 80 65 20 90 70 80 95 95
5-O-Glucuronide - - - Trace - - - - - - - -
7-O-Glucuronide 50 50 - 70 20 35 80 10 30 20 5 5
4′-O-Glucuronide - - - - - - - - - - - -
Isorhamnetin 1A1 1A3 1A4 1A6 1A7 1A8 1A9 1A10 2B4 2B7 2B15 2B17
Isorhamnetin 80 35 100 100 90 100 95 95 100 100 100 100
5-O-Glucuronide - - - - 10 - 5 Trace - - - -
7-O-Glucuronide - 50 - - Trace - - Trace - - - -
3-O-Glucuronide (20) (15) - - - - - (5) - - - -
4′-O-Glucuronide (20) (15) - - - - - (5) - - - -
Kaempferol 1A1 1A3 1A4 1A6 1A7 1A8 1A9 1A10 2B4 2B7 2B15 2B17
Kaempferol 40 90 100 60 75 90 75 100 95 100 100 100
5-O-Glucuronide 5 Trace - 30 10 Trace 10 Trace - Trace - -
7-O-Glucuronide 50 10 - 10 15 5 15 Trace 5 Trace - -
3-O-Glucuronide - - - - - - - - - - - -
4′-O-Glucuronide 5 Trace - Trace - 5 Trace Trace - Trace - -
Quercetin 1A1 1A3 1A4 1A6 1A7 1A8 1A9 1A10 2B4 2B7 2B15 2B17
Quercetin 25 55 100 95 100 100 70 95 100 90 100 100
5-O-Glucuronide - - - Trace - - - - - Trace - -
7-O-Glucuronide 5 25 - 5 - Trace 30 5 - - - -
3-O-Glucuronide - - - - - - - - - - - -
4′-O-Glucuronide 10 5 - - - Trace - Trace - - - -
3′-O-Glucuronide 60 15 - - - Trace - Trace - 10 - -