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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Mol Immunol. 2011 Aug 19;49(1-2):64–74. doi: 10.1016/j.molimm.2011.07.021

Figure 6. The effects of PI3K, MEK, JNK and p38 inhibitors on TNFα- or HA-mediated β-arrestin 1 and 2 expression in FLS.

Figure 6

FLS were isolated and cultured from DBA/1J mice. Cells were pretreated with or without the various inhibitors for 1 h followed by stimulation with TNFα or HA for 24 h. TNFα- (A) or HA- (B) mediated increases of β-arrestin 1 and 2 expression in FLS were determined. α-Tubulin was used as an internal control. Data represent means ± S.E from three independent experiments. *p<0.05 compared to unstimulated cells. #p<0.05 compared to TNFα or HA stimulation group.