Table 2.
Molecular weight (kDa) | Origin | Enzyme |
---|---|---|
37 | Extracellular shedding of membrane CD23 at position Ala80 |
in vivo: ADAM10 and MMP9 in vitro: ADAM10, ADAM8 and ADAM 33 |
33 | Extracellular shedding of membrane CD23 at position Arg101 |
in vivo: ADAM10 and MMP9 in vitro: ADAM10, ADAM8 and ADAM 33 |
28–29 | Intracellular processing of newly synthesized CD23 protein | Not defined |
25–27 | Proteolytic cleavage/degradation products of 33kDa and 37kDa sCD23 | Not defined |
16–17 | Extracellular cleavage of membrane CD23 at Ser155 and Glu298 | Der p1 |