Table 1.
Clinical characteristics of study sample.
| Demographics | |
| Average age at DCM diagnosis | 43.6 ±13.4 years, range 16–76 |
| Familial dilated cardiomyopathy | N = 32 (55%) |
| Previous Resequencing Studies3,5–9 | |
| LMNA point mutation negative | N = 58 (100%) |
| Point mutation negative in 15 other DCM genes | N = 44 (76%) |
| Clinical Features | |
| Arrythmia/Conduction System Disease | |
| Conduction system disorder | N = 58 (100%) |
| Any arrhythmia | N = 45 (78%) |
| Pacemaker | N = 13 (22%) |
| Implantable cardiac defibrillator | N = 38 (66%) |
| Sudden death during disease course | N = 14 (24%) |
| Myocardial Failure | |
| Heart failure | N = 52 (90%) |
| Heart transplant or ventricular assist device | N = 13 (22%) |
| Death (without transplant or ventricular assist device) | N = 10 (17%) |