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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Ann Neurol. 2011 Oct;70(4):606–615. doi: 10.1002/ana.22476

Fig 5. NOX2 deficiency in marrow derived cells reduces hemorrhagic transformation more than NOX2 deficiency in the brain.

Fig 5

A: Representative images show the severity of hemorrhagic transformation (HT) after experimental stroke. Mice lacking NOX2 in marrow derived cells (X-CGD to WT) had the least severe HT compared to mice with intact NOX2 in marrow derived cells (WT to X-CGD and WT to WT). B: Mice lacking NOX2 in either the brain (WT to X-CGD) or marrow (X-CGD to WT) experienced less severe HT compared to wildtype mice receiving wildtype marrow (WT to WT), but X-CGD to WT mice had the least severe HT. (n=6/group, *P<0.05 vs. WT to WT, **P<0.05 vs. WT to WT and WT to X-CGD)