Fig. 1.

A, Change (after GH treatment to before GH treatment) in fat (light gray bars) and lean mass (dark gray bars) as measured by dual-energy x-ray absorptiometry (mean ± sem). B, Changes in fat and lean mass for each patient (2–8) after treatment. Light gray bars, Fat mass; dark gray bars, lean mass. No body composition data for patient 1 was available for analysis. C, Mean ± sem serum levels of IGF-I at pre- (white bars) and post-GH substitution (black bars). *, P < 0.05 in a two-tailed paired t test. D, IGF-I serum level changes before and after GH treatment in individual patients (1–8).