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. 2011 Oct 25;2(10):81. doi: 10.1258/shorts.2011.011112

Table 1.

Study characteristics of reminder and recall studies

Paper Study period Setting and population Design Quality Intervention Outcome
Abramson et al.13 1993 Public health centre and children's hospital continuity clinic, Forsyth County, North Carolina, USA; low socioeconomic status Randomized controlled trial 23 1. Usual care (control group) vs.
2. Postcard reminders followed by telephone reminders
Age appropriate immunisations (DTP/OPV/Hib) at 7 months of age 1 vs. 2, net change = 19% (P <0.00001)
Alemi et al.14 1993–1994 Paediatric outpatient clinic, Cleveland, USA; children under 6 months of age at recruitment; urban; predominantly ethnic minorities; low socioeconomic status Controlled intervention trial 22.5 1. Usual care (control group) vs.
2. Computer-generated telephone reminders and recalls
On time immunisation with complete series (DTP/OPV/MMR/Hib): 1 vs. 2, net change = 24.4% (P = 0.0005)
Alto et al.15 1991 Family practice clinic, Colorado, USA; children between 2 months and 7 years old; low socioeconomic status Randomized controlled trial 26 1. Usual care (control group) vs.
2. Specific postcard reminders followed by telephone reminders
Up to date with DTP/OPV/MMR/Hib vaccinations: 1 vs. 2, net change = 8% (P <0.011)
Daley et al.16 2000 Primary Care Clinic, Denver, Colorado, USA; Predominantly Medicaid and uninsured patient population; Children aged 6 weeks to 22 months Randomized controlled trial 29.5 1. Usual care (control group) vs.
2. Reminder letter followed by telephone recall 10 days later
Immunisation with one or more doses of PCV7: 1 vs. 2, net change = 2.8% (95% confidence interval –1.8% to 7.4%)
Dini et al.17 1993–1996 County health department, Denver, USA; children aged 60–90 days who had received the first dose of DTP and/or IPV Randomized controlled trial 25 1.Usual care (control group) vs.
2. Telephone messages vs.
3. Letter reminders vs.
4. Telephone messages followed by letters
Completed immunisation series by 24 months of age 1 vs. any intervention net change = 8.3% (RR (rate ratio) = 1.21; CI (confidence interval) = 1.01-1.44). 1 vs. 2 net change = 8.4%, 1 vs. 3 net change = 7.3%, 1 vs. 4 net change = 9%
Hawe et al.18 Not reported Local government-operated public vaccination clinic, Ballarat, Australia, 259 children due for measles vaccination aged 12 months Randomized controlled trial 26.5 1. Usual reminder card
2.Health belief model reminder card
Usual card group 67% vaccinated Health belief model card group 79% 12% difference (0.026)
Irigoyen et al.19 1997 Paediatric clinic, New York, USA; children aged 4–18 months Controlled intervention trial 26.5 1. Usual care (control group) vs.
2. Postcard reminder vs.
3. Telephone reminder vs.
4. Postcard plus telephone reminder
No significant difference in vaccination coverage by study group
Irigoyen et al.20 2001 Five inner-city community paediatric practices, New York, USA; children aged 6 weeks to 15 months due or late for DTP Randomized controlled trial 27 1. Usual care (control group) vs.
2. Continuous postcard reminders (as many as needed) vs.
3. Limited postcard reminders (up to 3)
Up to date 4:3:1:3 at 3 months post randomization 1 vs. 2 net change = 5.3% (P < 0.01), 1 vs. 3 net change = 1.5% (not significant) Up to date 4:3:1:3 at 6 months post randomization 1 versus 2 net change = 4.9% (p < 0.05), 1 vs. 3 net change = 2.8% (not significant) Multivariate analysis showed reminders had no independent effect on immunization outcomes
Kempe et al.21 1999 Outpatient paediatric clinic, urban teaching hospital, Denver, Colorado, USA; children aged 5–17 months; low socioeconomic status; highly transient population Randomized controlled trial 26.5 1.Usual care (control group) vs.
2. Postcard reminder plus telephone reminders
UTD at 12 months 1 vs. 2 net change 12% (P = 0.07)
LeBaron et al.22 1996–1998 Fulton County, Georgia, USA; children born between 1 July 1995 and 6 August 1995 Randomized controlled trial 25 1. Usual care (control group) vs.
2. Automated telephone or mail reminder recall vs.
3. In-person telephone, mail or home visit recall vs.
4. Auto-dialler with outreach backup
UTD with DTP/OPV/MMR/Hob (4:3:4:1) at 24 months of age 1 vs. 2 net change = 6% (P < 0.05), 1 vs. 3 net change = 3% (not significant), 1 vs. 4 net change = 4% (not significant)
Lieu et al.23 1994–1995 Managed care organization, Northern California, children aged 20–24 months old, n = 149 control group, n = 172 intervention group Randomized controlled trial 23.5 1. Usual care (control group) vs.
2. Patient recalls via computer-generated personalized letter
MMR by age 24 months, 1 vs. 2 = 19% net change (P < 0.001)
Lieu et al.24 1996–1997 Health Maintenance Organization, California, USA; under-immunised 20-month old children Randomized controlled trial 23 1. Automated telephone reminder vs.
2. Letter reminder vs.
3. Automated telephone reminder followed by a reminder letter 1 week later vs.
4.Letter reminder followed by an automated telephone message 1 week later
Proportion of under-immunised children who received any needed vaccinations by age 24 months, 1 vs. 2 no net change; 1 vs. 4 net change 14% (P = 0.02); 2 vs. 4 14% (P = 0.01), 1 vs. 3 net change = 9% (P = 0.1), 2 vs. 3 net change 9% (P = 0.09)
Mason and Donnelly25 1998–1999 Local health authority, Wales, UK; children aged 21 months who had not received MMR vaccine Randomized controlled trial 24 1. Usual care vs.
2. Personal reminder letter and educational leaflet
Immunised with MMR at age 21–24 months of age 1 vs. 2, net change = 1.1% (95% CI –3.3–5.5); immunised with MMR at >24 months of age, 1 vs. 2 = 1.1% (95% CI –3.6–5.7)
Morgan et al.26 1996 South Glamorgan, Wales, UK; children aged between 9 months and 21 months Randomized controlled trial 27.5 1. Usual care (control group) vs.
2. Non-directive telephone call to child's health visitor vs.
3. Mailed reminder
Immunised with MMR 1 vs. 2 net change = –7%, 1 vs. 3 net change = –11%
Rodewald et al.27 1994–1995 Nine primary care practices, Rochester, New York, USA; 3015 infants Randomized controlled trial (two by two factorial design) 25.5 1. Usual care (control group)
2. Tracking/Outreach/prompting- lay outreach workers using postcards, telephone calls and home visits
3. Tracking/outreach
4. Prompting- during visits to primary care office, marking charts
UTD net change 1 vs. 2 = 21%; 1 vs. 3 21%; 1 vs. 4 = 2% (none showed significance); 1 vs. 2 plus 3 P < 0.001
Stehr-Green et al.28 1990 Public health clinics, Atlanta, Georgia, USA; Average age 8.7–9.2 months; n = 110 control group, n = 112 intervention group Randomized controlled trial 24.5 1. Usual care (control group) vs.
2. Automated telephone reminder (max 9 attempts)
DTP immunisation, 1 vs. 2 = 3% net change (non-significant)
Szilagyi et al.29 1993–1996 Three geographical regions of Monroe County, New York, USA; children aged up to 2 years Randomized controlled trial 24.5 1. Usual care 1993 (control group)
2. Staged intervention of increasing intensity letters, postcards or phone calls and outreach 1999
UTD with DTP/OPV/MMR/Hib 4:3:1:1 1 vs. 2 net gain = Monroe county 20%, suburbs 15%, inner city 29%, rest of city 17% (significance not stated)
Tollestrup and Hubbard30 1987 County health department clinics, Washington, USA; children aged up to 5 years Controlled intervention trial 23.5 1. Usual care (control group) vs.
2. Recall letter if 1 month overdue
DTP vaccination within 5 months, 1 vs. 2 net change = 18% (P < 0.01)
Vivier et al.31 1998 Primary care clinics, Rhode Island, USA; children enrolled in a managed care programme, up to the age of 6 years Randomized controlled trial 24 1. Usual care (control group) vs.
2. Telephone reminder vs.
3. Postal reminder vs.
4. Sequential postal/telephone reminders
Immunisations UTD, 1 vs. 2, net change = 11% (P > 0.05); 1 vs. 3, net change = 12% (P > 0.05); 1 vs. 4, net change = 14% (P > 0.05); 1 vs. 2–4 combined P < 0.05
Wilcox et al.32 1997 Philadelphia, Pennsylvania, USA; 1752 children aged 6–10 months Randomized controlled trial 24.5 1. Usual care (control group) vs.
2. Outreach
One immunisation received during study period 1 vs. 2 net change = 18% (P < 0.001); UTD with immunisations 1 vs. 2 net change –1% (not significant)
Yokley and Glenwick33 Not stated Public health clinic, Akron, Ohio, USA; children aged under 5 years; mean age 37 months; n = 183–195 in each group Group randomized trial by family 23.5 1. Usual care (control group) vs.
2. General postal patient reminder vs.
3. Specific postal patient reminder vs.
4. Specific postal patient reminder plus special out of hours clinics vs.
5. Specific postal patient reminder plus parent incentive lottery
Vaccinated with at least one antigen after 3 months: 1 vs. 2 = 3% net change (non-significant), 1 vs. 3 = 13% (non-significant), 1 vs. 4 = 16% (significant), 1 vs. 5 = 18% (significant)
Young et al.34 1978 Ohio, USA; 6-month old high-risk children Randomized controlled trial 21 1. Usual care (control group) vs.
2. Mailed reminder
One immunisation received during study period 1 vs. 2 net change = 16% (P = 0.02); UTD with vaccinations 1 vs. 2 net change = 12% (P = 0.06)