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CHD1 associates with Med1-containing Mediator in vivo. Immunoblots showing specific shRNA knockdown of Med1 and Med23 subunits of Mediator in 293T cells (left panels) and Med1-dependent coimmunoprecipitation of Mediator by targeted immunoprecipitation of CHD1 (right panel). Subunits representing the head (Med6), middle (Med7), and tail (Med14) modules of Mediator are blotted.
