FIG. 5.—

Dosage balance for three different network sizes is shown. Larger network size corresponds to prolonged retention due to comparatively larger fitness effects of individual gene losses as well as the mutational opportunity to lose a gene from link loss being lower because there are more links to be lost before an entire gene is nonfunctionalized. The fitness penalty for links out-of-balance is 0.4. These curves were generated using the parameter values in table 1 for the network model and were fit with the parameter values from the loss model in table 2.