Table 1.
Distribution pattern of P. falciparum pfcrt haplotypes over time
| Haplotype | Sequence | Frequency of haplotypes (%) | |||
|---|---|---|---|---|---|
| Anadhurapura | Seven districts | ||||
| 1996 | 1997 | 1998 | 2004–2006 | ||
| CVMNK | TGTGTAATGAATAAA (six samples sequenced) | 4 (31%) | 2 (13%) | 0 (0) | 0 (0) |
| SVMNT | AGTGTAATGAATACA (36 samples sequenced)* | 9 (69%) | 13 (81%) | 29 (97%) | 24 (100%) |
| CVIET | TGTGTAATTGAAACA (one sample sequenced) | 0 (0) | 1 (6%) | 1 (3%) | 0 (0) |
1996–1998 = Fisher–Freeman–Halton test (P = 0.007). 2004–2006 = Cochran–Armitage test (CVMNK and SVMNT; P = 0.004).
*
One sample was sequenced as AGTGTGATGAATACA.