Table 3.
Hematologic and biochemical profiles in acute hepatitis A and scrub typhus patients, South Korea*
| Characteristic | Acute hepatitis A (n = 104) | Scrub typhus (n = 197) | P |
|---|---|---|---|
| Major liver enzymes | |||
| ALP (U/L) | 141 ± 71 (33–703) | 126 ± 104 (38–583) | 0.166 |
| < 129 | 51 (49.0) | 142 (72.8) | < 0.001 |
| ≥ 130 | 53 (51.0) | 53 (27.2) | |
| Bilirubin (mg/dL) | 5.12 ± 3.26 (0–20) | 1.00 ± 1.01 (0–7) | < 0.001 |
| < 1.2 | 10 (9.6) | 164 (83.3) | < 0.001 |
| ≥ 1.3 | 94 (90.4) | 33 (16.8) | |
| ALT (U/L) | 2,618 ± 2,203 (16–10,097) | 96 ± 121 (12–1,221) | < 0.001 |
| < 39 | 2 (1.9) | 50 (25.4) | < 0.001 |
| 40–499 | 11 (10.6) | 145 (73.6) | |
| ≥ 500 | 91 (87.5) | 2 (1.0) | |
| Other laboratory findings | |||
| Leukocytes (/μL) | 5,582 ± 2,574 (1,070–17,180) | 8,017 ± 3,804 (1,850–20,000) | < 0.001 |
| Platelets (/μL) | 176 ± 90 × 103 (21–550 × 103) | 145 ± 70 × 103 (17–585 × 103) | 0.003 |
| Hemoglobin (g/dL) | 14.5 ± 1.6 (10.6–18.7) | 12.6 ± 1.7 (7.0–17.6) | < 0.001 |
| CPK (U/L) | 184 ± 517 (0–3,818) | 241 ± 561 (9–6,114) | 0.464 |
| LDH (U/L) | 2,024 ± 2,679 (189–18,100) | 884 ± 339 (290–3,510) | < 0.001 |
| CRP (mg/dL) | 1.07 ± 0.87 (0–4) | 9.09 ± 7.37 (0–78) | < 0.001 |
| ESR (mm/hr) | 16 ± 17 (2–85) | 20 ± 17 (2–86) | 0.087 |
| γ-GGT (U/L) | 309 ± 192 (9–1,022) | 129 ± 159 (15–1,141) | < 0.001 |
| AST (U/L) | 2,486 ± 3,176 (42–10,875) | 112 ± 122 (17–1,164) | < 0.001 |
| ALT:LDH | 36.88 ± 63.22 (6–487) | 1.60 ± 1.84 (2–20.9) | < 0.001 |
| Albumin (g/dL) | 3.96 ± 0.38 (2.80–4.90) | 3.63 ± 0.57 (2.10–4.99) | < 0.001 |
| Protein (g/dL) | 6.77 ± 0.67 (5.3–8.2) | 6.51 ± 0.82 (3.2–8.6) | 0.004 |
| Creatinine (mg/dL) | 1.0 ± 0.7 (0.6–6.8) | 1.2 ± 0.7 (0.4–5.1) | 0.03 |
*
Values are no. (%) or mean ± SD. ALP = alkaline phosphatase; ALT = alanine aminotransferase; CPK = creatine phosphokinase; LDH = lactate dehydrogenase; CRP = C-reactive protein; ESR = erythrocyte sedimentation rate; γ-GGT = γ-glutamyl transpeptidase; AST = aspartate aminotransferase.