Table 2.
Variable | OR (95% CI) | P | |
---|---|---|---|
Factors predisposing for severity | |||
Age | 1.07 (1.02–1.12) | 0.003 | |
Diabetes mellitus | 5.55 (1.12–27.48) | 0.036 | |
Hypertension | 2.08 (0.66–6.56) | 0.211 | |
Other less frequent chronic diseases† | 3.65 (1.05–12.71) | 0.042 | |
Visit without diagnosis‡ | 0.32 (0.11–0.93) | 0.036 | |
Serum OPN (> 100 ng/mL) | 3.35 (1.16–9.69) | 0.026 | |
Laboratory markers indicating current severity | |||
Serum OPN (> 100 ng/mL) | 2.96 (1.09–8.04) | 0.034 | |
Hemoglobin (≤ 10 g/dL) | 32.08 (2.61–393.87) | 0.007 | |
Platelets (≤ 100,000/mm3) | 1.45 (0.49–4.26) | 0.499 | |
Serum albumin (≤ 3.0 g/dL) | 1.61 (0.49–5.32) | 0.435 | |
CRP (> 10 mg/dL) | 3.47 (1.18–10.16) | 0.023 | |
Serum Cr > 2.0 mg/dL | 6.98 (0.28–174.71) | 0.237 | |
AST > 40 IU/L | 2.01 (0.23–17.62) | 0.528 | |
ALT > 40 IU/L | 1.07 (0.24–4.66) | 0.934 | |
Potassium ≤ 3.5 mmol/L | 1.51 (0.50–4.57) | 0.468 |
OR = odds ratio; CI = confidence interval; OPN = serum osteopontin; CRP = C-reactive protein; AST = aspartate aminotransferase; ALT = alanine aminotransferase.
“Other less frequent chronic diseases” include congestive heart failure, cerebrovascular disease, chronic liver disease, asthma, and chronic obstructive pulmonary disease.
Patients who visited the hospital by themselves or who were referred from primary hospitals without initial clinical suspicion of scrub typhus.