Table 7.

Comparison between AIDS-related imported Histoplasma capsulatum and H. duboisii histoplasmosis, France^*

Characteristic	H. capsulatum, pre-HAART era	H. capsulatum, HAART era	H. duboisii
No.	40	64	17
Mean age (years)	38	40	34
No. men	78	58	71
Clinical features, %
Fever	88	84	58
Adenopathy	49	63	53
Hepatosplenomegaly	48 (HM), 36 (SM)	43 (HM), 44 (SM)	12
Pulmonary symptoms	60	34	0
Skin	56	44	59
Bone	0	0	18
Abdominal	40	36	12
Diagnosis tools, %
Direct examination	95	94	100
Culture	78	81	64
Blood culture	35	54	12
Outcome, %
Death	53	22	24
Relapse	5	3	12

^*AIDS = acquired immunodeficiency syndrome; HAART = highly active antiretroviral therapy; HM = hepatomegaly; SM = splenomegaly. Data for H. duboisii-infected patients are from Loulergue and others.¹⁹