(b)

T-cells immunophenotypes	Late Presenters (CD4 T cell <  350 and/or AIDS defining event)		P
	No (145, 53%)	Yes (130, 47%)
CD4+ T cells %*	28 (23–35)	14 (10–21)	0.0001
CD8+ T cells %*	45 (38–54)	57 (51–63)	0.0001
CD4+CD127+ cells %*	19 (12–24)	7 (4–12)	0.0001
CD8+CD127+ cells %*	10 (8–15)	11 (7–19)	0.346
CD4+CD95+ cells %*	2 (1–4)	2 (1–3)	0.898
CD8+CD95+ cells %*	2 (1–3)	3 (2–5)	0.0001
CD8+CD38+ cells %*	5 (2–9)	9 (3–18)	0.0001
CD8+CD38+CD45R0+ cells %*	9 (5–16)	15 (10–25)	0.0001

Data are presented as *median, (interquartile range, IQR) and °absolute number, (%). IDUs: injection drug users; migrants: people who were born outside the European community (including people from Eastern Europe, Africa, Asia, and Latin America); HCV: hepatitis C virus.

Comparison between categorical variables was assessed by Pearson's Chi square and between continuous variables by nonparametric Mann-Whitney U-test. P < 0.05 was considered to denote statistical significance.