Table 3.
Density of liver parenchyma at baseline and follow-up (in HU) and dHU (baseline−follow-up) for all patients, unblinded to chemotherapy (FOLFOX and FOLFIRI)
| Density of liver parenchyma |
dHU (mean HU ± SD) | p value | |||
|---|---|---|---|---|---|
| Baseline (mean HU ± SD) | Follow-up (mean HU ± SD) | ||||
| FOLFOX + FOLFIRI | Plain | 56.2 ± 8.2 | 54.9 ± 13.2 | −1.3 ± 9.0 | 0.24 n.s. |
| Arterial | 76.7 ± 16.0 | 71.1 ± 20.4 | −5.59 ± 22.2 | 0.1 n.s. | |
| Portal venous | 106.2 ± 17.3 | 93.8 ± 18.4 | −12.4 ± 15.5 | 0.0001 s. | |
| FOLFOX | Plain | 58.8 ± 6.4 | 59.6 ± 4.9 | 0.8 ± 5.6 | 0.32 n.s |
| Arterial | 75.7 ± 11.9 | 71.2 ± 15.2 | −4.5 ± 13.3 | 0.12 n.s. | |
| Portal venous | 107.1 ± 15.6 | 97.5 ± 11.9 | −9.6 ± 15.0 | 0.01 s. | |
| FOLFIRI | Plain | 53.7 ± 9.2 | 50.3 ± 17.1 | −3.7 ± 11.6 | 0.15 n.s. |
| Arterial | 77.8 ± 19.7 | 71.0 ± 25.2 | −6.7 ± 29.0 | 0.20 n.s. | |
| Portal venous | 105.0 ± 19.7 | 89.3 ± 24.0 | −15.6 ± 16.6 | 0.005 s. | |
n.s., not significant; s., significant.