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. 2011 Jun 14;22(10):1179–1190. doi: 10.1089/hum.2011.069

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Copyright 2011, Mary Ann Liebert, Inc.

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FIG. 6. — Restoration of cone-mediated optomotor behavior in Gucy2e^–/– treated eyes. Shown is the photopic visual acuity and contrast sensitivity measurements in two untreated Gucy2e^–/– mice (animals 1 and 2), and six mice treated with high-titer vector (animals 3–8) 4 months post treatment. Results are presented for each animal and averaged per group in the right-hand graphs. (a) Robust improvement in visual acuity was consistently observed in treated eyes (p<0.0001, one-way ANOVA). (b) A significant improvement in contrast sensitivity was detected in treated eyes (p<0.05, one-way ANOVA). OD, right eye; OS, left eye.