FIGURE 1.

Duration of tamoxifen use versus age for the amenorrheic tamoxifen users tested with the forced-response color-naming paradigm detailed in Eisner & Incognito (2006).¹⁸⁴ Open symbols represent subjects who called the threshold-level incremental test stimulus “white", and filled symbols represent subjects who called this stimulus “lavender". The test stimulus was a 3° diameter short-wavelength (440 nm) disc that was square-wave modulated at a rate of 1.5 Hz and was centered within an adapting background stimulus. The background was a moderately bright (3.6 log troland) 11° diameter, yellow (580 nm) disc viewed for at least 5 minutes. The horizontal dashed line signifies 2 years of tamoxifen use. (Data from three tamoxifen users who called the stimulus “blue” are omitted. For one of these subjects, the sensitivity was grossly reduced;¹⁸⁴ the other two subjects were ages 56.8 and 59.5 years, and used tamoxifen for 4.0 and 4.9 years, respectively.) This graph has not been published previously.