Table 1.

Mutants and primers of the binding sites in human MMP-9 promoter used in site-directed mutagenesis

Binding site	Mutant	Primer sequence
NF-κB site 1	g1389c	5′-ggttgccccagtgcaattccccagcct-3′ (sense)
NF-κB site 2	g1664c	5′-ccaagggatggggcatccctccagctt-3′ (sense)
AP-1 site 1	c1460t_a1461g	5′-gggagaggaagctgagttgaagaaggctgtcaggga-3′ (sense)
AP-1 site 2	c1918t_a1919g	5′-acacaccctgacccctgagttggcacttgcctg-3′ (sense)
SP-1 site	g1940t_g1941t	5′-tgcctgtcaaggaggtttggggtcacaggagc-3′ (sense)