Table II. Minimal required translation and translocation machinery is MAM associated and induced by HCMV infection at late times.
| UniProt ID | Proteina | Descriptionb | Forward |
Reverse |
|---|---|---|---|---|
| SILAC-HCMV-Infected/Uninfected average±S.D. (P)c | SILAC-Uninfected/HCMV-Infected average±S.D. (P)c | |||
| Translation/Translocation Machinery (Required Minimal Components) | ||||
| P61619 | SEC61A1 | Translocon protein | 4.61 ± 0.49 (18) | 0.3 ± 0.02 (22) |
| P60468 | SEC61B | Translocon protein | 5.59 ± 0.34 (3) | 0.28 ± 0.02 (6) |
| P04843 | RPN1 | OST protein | 4.51 ± 0.41 (51) | 0.3 ± 0.02 (66) |
| P04844 | RPN2 | OST protein | 3.93 ± 0.27 (57) | 0.33 ± 0.02 (41) |
| P61803 | DAD1 | OST protein | 4.07 ± 0.13 (6) | 0.33 ± 0.02 (7) |
| P39656 | DDOST | OST protein | 3.86 ± 0.3 (22) | 0.33 ± 0.03 (26) |
| P61011 | SRP54 | Subunit of signal recognition particle | 3.98 ± 0.96 (3) | 0.41 ± 0.02 (2) |
| O76094 | SRP72 | Subunit of signal recognition particle | 3.71 ± 0.54 (2) | ND |
| Q9UHB9 | SRP68 | Subunit of signal recognition particle | ND | 0.4 (1) |
| P08240 | SRPRA | Subunit of signal recognition particle receptor | 7.4 ± 0.97 (13) | 0.19 ± 0.05 (14) |
| Q9Y5M8 | SRPRB | subunit of signal recognition particle receptor | 6.13 ± 0.44 (10) | 0.26 ± 0.02 (16) |
| Translation/Translocation Machinery (Accessory Components) | ||||
| Q99442 | SEC62 | Translocon protein | 5.98 ± 1.11 (6) | 0.19 ± 0.03 (5) |
| Q9UGP8 | SEC63 | Translocon protein | 3.23 ± 0.41 (13) | 0.33 ± 0.08 (12) |
| P43307 | SSR1 (TRAPA) | Translocon associated protein | 4.67 ± 0.54 (7) | 0.33 ± 0.03 (10) |
| Q9UNL2 | SSR3 (TRAPG) | Translocon associated protein | 5.41 ± 0.21 (3) | 0.26 ± 0.02 (3) |
| P51571 | SSR4 (TRAPD) | Translocon associated protein | 5.1 ± 0.35 (15) | 0.27 ± 0.01 (11) |
a Name given by UniProt database.
b Relevant descriptions from the literature.
c Average ratio ± standard deviation (number of identified unique peptides).