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Changes in ionized calcium (A), CTX (B), P1NP (C), and sclerostin (D) during PTH infusion. Ionized calcium and CTX increased linearly whereas P1NP decreased linearly during PTH infusion (P < 0.001 for all). Sclerostin declined by 6 h and was maintained at a reduced level throughout the infusion (P = 0.007).
