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Top: E vs. PCWP in individual HFpEF patients with superimposed linear regressions. E demonstrated a degree of preload dependence which was similar between individual HFpEF patients. Bottom: e’ vs. PCWP in individual HFpEF patients with superimposed linear regressions. e’ varied greatly between individual HFpEF patients accounting for the broad variability observed in individual E/e’ slopes as preload was manipulated.
