Table 3.
Coefficients of the intercepts and slopes of the eGFR progression analysis
| Coefficient (95% CI) | P | |
|---|---|---|
| Variables that affect the intercept | ||
| Intercept | 80.9 (80.7, 81.1) | <0.01 |
| Age (decades) | −5.1 (−5.2, −5.0) | <0.01 |
| Female gender (versus male) | 1.2 (1.0, 1.4) | <0.01 |
| Race/ethnicity | ||
| African American | 4.1 (3.6, 4.6) | <0.01 |
| Hispanic/Latino | 3.7 (3.2, 4.2) | <0.01 |
| Caucasian (referent) | 1.0 | |
| other | 1.7 (1.0, 2.3) | <0.01 |
| missing | 1.0 (0.7, 1.2) | <0.01 |
| Diabetes | 2.9 (2.6, 3.2) | <0.01 |
| Systolic BP, time-weighted (per 10 mmHg) | 0.2 (0.2, 0.3) | <0.01 |
| HDL, time-weighted (per 10 mg/dl) | 0.2 (0.1, 0.3) | <0.01 |
| Variables that affect the slope | ||
| Time (years) | −1.4 (−1.4, −1.3) | <0.01 |
| Age (decades) | −0.2 (−0.2, −0.2) | <0.01 |
| Female gender (versus male) | −0.8 (−0.8, −0.7) | <0.01 |
| Diabetes | −0.8 (−0.9, −0.7) | <0.01 |
| Congestive heart failure | −0.3 (−0.5, −0.2) | <0.01 |
| Systolic BP, time-weighted (per 10 mmHg) | −0.2 (−0.2, −0.2) | <0.01 |
| HDL, time-weighted (per 10 mg/dl) | 0.1 (0.0, 0.1) | <0.01 |
The intercept coefficients represent the within-subgroup difference in baseline estimated GFR (eGFR). The slope coefficients represent the rate of change of eGFR per year, where a negative number represents a decline in kidney function. CI, confidence interval.