Table 3. Treatment characteristics of patients with late recurrent TB*, California 1993–2007.
| Characteristic | Recurrent TB*n (%) | Single episode TBn (%) | Unadjusted hazard ratio (95% CI) | p-value | |
| No. | 148 | 23,369 | |||
| Initial drug regimen | Standard 4drug | 120 (81) | 19,862 (85) | Ref | 0.021 |
| Two-drug IR | 7 (5) | 361 (2) | 2.46 (1.15–5.26) | 0.591 | |
| Other regimen | 21 (14) | 3,146 (13) | 0.88 (0.55–1.40) | ||
| Provider type‡ | Health dept | 90 (61) | 12,552 (54) | 1.38 (0.99–1.92) | 0.0553 |
| Private/other | 24 (16) | 6,445 (28) | Ref | ||
| Both | 34 (23) | 4,357 (19) | 1.30 (0.88–1.90) | 0.186 | |
| Anti-TB therapy administration‡ | SAT only | 51 (34) | 7,324 (31) | 0.85 (0.60–1.19) | 0.343 |
| DOT only | 59 (40) | 11,049 (47) | Ref | ||
| DOT+SAT | 35 (24) | 4,597 (20) | 1.33 (0.91–1.95) | 0.137 | |
| Unk | 3 (2) | 399 (2) | |||
| Time on anti-TB therapy, months (median) | 9.02 mo. | 8.34 mo. | 1.03 (1.0–1.07) | 0.052 | |
| Documented sputum culture conversion | Yes | 130 (88) | 18,463 (79) | 1.86 (1.03–3.36) | 0.0395 |
| No | 12 (8) | 2,657 (11) | Ref | ||
| Unk | 6 (4) | 2,249 (10) | |||
| Culture conversion within 60 days | Yes | 47 (32) | 9,306 (40) | Ref | |
| No | 79 (53) | 9,098 (39) | 1.58 (1.10–2.26) | 0.0137 | |
| Unk | 22 (15) | 4,965 (21) |
Definition of abbreviations: Ref = reference group; Unk = unknown or missing; Standard 4drug = initial treatment with standard four drug regimen (isoniazid, rifampin, pyrazinamide, ethambutol); Two-drug IR = initial treatment with isoniazid and rifampin only; DOT = directly observed therapy; SAT = self-administered therapy.
*Characteristic present in the first episode of patients with late recurrent TB (see text for details).
‡
3-level variable comparison.