Table 2. HapMap variation detection sensitivity after duplicate removal.
Pool | Pool | Pool | Pool | Pool | |
of 1 | of 2 | of 10 | of 20 | of 50 | |
(1089)a | (1459)a | (1999)a | (2067)a | (2145)a | |
PCR | 26.26 | 87.46 | 92.35 | 96.27 | 95.80 |
aHC | 97.15 | 85.33 | 96.60 | 97.82 | 94.41 |
sHC | 94.12 | 95.07 | 98.30 | 98.16 | 96.88 |
This table contains the percentage of the known HapMap variants with at least one non-reference allele in the pool that each pool and enrichment method discovered (true positives). The false negative rate is 100 minus this value.
: number of non-reference HapMap variants in pool.