Table 4. Performance of bbTM matrices in detecting homologs of -barrel membrane protein sequences from the “true-positive” database.
e-value | bbTMall | bbTMin | bbTMout | Blosum62 | Phat7573 | Slim161 | Pam250 |
10 | 49 | 62 | 56 | 5 | 48 | 46 | 8 |
10 | 116 | 106 | 121 | 32 | 121 | 119 | 41 |
10 | 122 | 121 | 129 | 42 | 133 | 130 | 79 |
10 | 128 | 127 | 143 | 83 | 141 | 143 | 102 |
10 | 138 | 131 | 147 | 95 | 148 | 145 | 107 |
10 | 146 | 139 | 168 | 109 | 176 | 170 | 119 |
10 | 153 | 144 | 206 | 120 | 200 | 202 | 136 |
10 | 191 | 166 | 245 | 126 | 272 | 260 | 202 |
Cumulative number of proteins identified as homologs of 20 template -barrel membrane proteins at different -values obtained from Blast searches against the “true-positive” database of 3,079 sequences of -barrel membrane proteins.