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. 2011 Nov 1;6(11):e27022. doi: 10.1371/journal.pone.0027022

Figure 3. Changes of key stereometric parameters at high altitude.

Figure 3

Intraindividual changes (expressed as ratios) of key stereometric parameters at altitude show statistically significant but reversible optic disc edema at high altitude. (A) Mean retinal nerve fiber layer (RNFL) thickness, (B) rim volume, (C) RNFL cross sectional area and (D) maximum contour elevation are significantly increased between day2 and day4 of altitude exposure (p<0.05). Individual measurements at baseline prior to the climb (BL1) were normalized to display intraindividual ratios of values at high altitude/BL1. Blue dashed lines indicate BL1 level; red lines indicate mean; whiskers indicate 95% confidence interval; number of subjects: nday1 = 14, nday2–3 = 16, nday4 = 18.