Figure 1. Top, Cartoon representation of the N-terminal structure of human apoE3 (PDB code: 1LPE) indicating the location of the mutations; protein is depicted in side and top view.

Bottom, SDS-PAGE analysis of the recombinant apoE3 variants and wild-type protein. Molecular mass marker bands are indicated. Images were prepared using PyMol 1.3 (www.pymol.org).