Table 5. Parameters calculated from DLS experiments for apoE3 variants (Figure 8).

apoE3	Diameter (I)**Peak 1	Diameter (I)**Peak 2	Diameter (V)**
WT	10.9±1.4	68 ±7	10.4±1.7
R145C	13.7±3.6	137±67	11.3±3.1
K146E	10.6±1.4	58±6	10.1±1.7
R136S	17.1±1.2	n/d*	16.9±2.1

Calculated particle diameters are given in nm. Errors indicate peak width. Peak 2 corresponds to ∼1% of the total mass of the protein sample and indicates higher order aggregates. Units are in nm. Values are means ± SD from three experiments.

*non-detected.

**I =  diameter calculated based on the distribution of intensities of scattering, V =  diameter calculated after normalization of the scattering distribution based on particle volume occupancy.