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. 2011 Nov 1;6(11):e27141. doi: 10.1371/journal.pone.0027141

Figure 2. L2-specific antibody titers induced by vaccination of mice with capsomers.

Figure 2

Two weeks after the third immunization with GST-HPV16L1Δ, GST-HPV16L1Δ-L2x3 or Cervarix®, two-fold dilutions of serum from immunized mice were tested by ELISA for L2 specific antibodies. Microtiter plates were coated with either HPV16 L2 amino acids 11–200 (A), or the 17–38 L2 peptide (B), or HPV18 L2 full length protein (C), or HPV31 L2 17–36 peptide (D), or HPV31 full length protein (E) or HPV35 L2 17–36 peptide (F), or HPV45 L2 16–35 peptide (G), or HPV58 L2 16–35 peptide (H), and then incubated with diluted serum samples (1∶50 as the initial dilution; two-fold serial dilutions).