Table 2.
Univariate and Multivariate Regression Analyses*
| Variable† | Univariate Analysis | Multivariate Analysis‡ | ||
|---|---|---|---|---|
| Regression Coefficient (95% CI) | P Value | Regression Coefficient (95% CI) | P Value | |
| Anterior–posterior spine BMD | ||||
| Age | −0.0017 (−0.0049 to 0.0014) | >0.2 | 0.0006 (−0.0020 to 0.0033) | >0.2 |
| Age at menarche | −0.0200 (−0.0325 to −0.0076) | 0.002 | −0.0158 (−0.0266 to −0.0049) | 0.005 |
| Time since last menstrual period | −0.0013 (−0.0019 to −0.0007) | <0.001 | −0.0014 (0.0019 to −0.0008) | <0.001 |
| Weight | 0.0085 (0.0057 to 0.0113) | <0.001 | 0.0052 (0.0014 to 0.0091) | 0.008 |
| Height | 0.0050 (0.0022 to 0.0078) | 0.001 | 0.0020 (−0.0013 to 0.0051) | >0.2 |
| Wrist size | 0.0423 (0.0145 to 0.0700) | 0.003 | 0.0135 (−0.0169 to 0.0439) | >0.2 |
| History of fracture | 0.0153 (−0.0276 to 0.0581) | >0.2 | 0.0127 (−0.0050 to 0.0304) | 0.158 |
| Lateral spine BMD | ||||
| Age | −0.0028 (−0.0055 to −0.0001) | 0.042 | −0.0008 (−0.0035 to 0.0020) | >0.2 |
| Age at menarche | −0.0049 (−0.0158 to 0.0061) | >0.2 | −0.0041 (−0.0150 to 0.0068) | >0.2 |
| Time since last menstrual period | −0.0008 (−0.0013 to −0.0003) | 0.005 | −0.0007 (−0.0014 to −0.0001) | 0.024 |
| Weight | 0.0065 (0.0038 to 0.0091) | <0.001 | 0.0049 (0.0009 to 0.0090) | 0.018 |
| Height | 0.0026 (−0.000006 to 0.0051) | 0.051 | −0.0019 (−0.0054 to 0.0016) | >0.2 |
| Wrist size | 0.0384 (0.0136 to 0.0631) | 0.003 | 0.0231 (−0.0111 to 0.0574) | 0.182 |
| History of fracture | 0.0007 (−0.0371 to 0.0385) | >0.2 | −0.0008 (−0.0194 to 0.0178) | >0.2 |
| Total hip BMD | ||||
| Age | −0.008 (−0.0119 to −0.0041) | <0.001 | −0.0060 (−0.0098 to −0.0023) | 0.002 |
| Age at menarche | −0.0134 (−0.0304 to 0.0037) | 0.123 | −0.0135 (−0.0281 to 0.0010) | 0.067 |
| Time since last menstrual period | −0.0016 (−0.0024 to −0.0008) | <0.001 | −0.0006 (−0.0014 to 0.0002) | 0.158 |
| Weight | 0.0115 (0.0076 to 0.0154) | <0.001 | 0.0108 (0.0055 to 0.0161) | <0.001 |
| Height | 0.0047 (0.0007 to 0.0087) | 0.023 | −0.000039 (−0.0046 to 0.0045) | >0.2 |
| Wrist size | 0.0161 (−0.0260 to 0.0582) | >0.2 | −0.0287 (−0.0741 to 0.0166) | >0.2 |
| History of fracture | 0.0340 (−0.0245 to 0.0924) | >0.2 | 0.0192 (−0.0050 to 0.0434) | 0.117 |
| Femoral neck BMD | ||||
| Age | −0.0083 (−0.0117 to −0.0049) | <0.001 | −0.0070 (−0.0103 to −0.0037) | <0.001 |
| Age at menarche | −0.0073 (−0.0229 to 0.0084) | >0.2 | −0.0087 (−0.0216 to 0.0042) | >0.2 |
| Time since last menstrual period | −0.0013 (−0.0020 to −0.0006) | <0.001 | −0.0003 (−0.0010 to 0.0004) | 0.184 |
| Weight | 0.0091 (0.0055 to 0.0128) | <0.001 | 0.0097 (0.0049 to 0.0144) | <0.001 |
| Height | 0.0032 (−0.0004 to 0.0069) | 0.084 | −0.0013 (−0.0053 to 0.0028) | >0.2 |
| Wrist size | 0.0141 (−0.0233 to 0.0515) | >0.2 | −0.0172 (−0.0576 to 0.0231) | >0.2 |
| History of fracture | 0.0131 (−0.0399 to 0.0662) | >0.2 | 0.0134 (−0.0081 to 0.0350) | >0.2 |
| Trochanter BMD | ||||
| Age | −0.0070 (−0.0102 to −0.0039) | <0.001 | −0.0054 (−0.0085 to −0.0023) | 0.001 |
| Age at menarche | −0.0062 (−0.0206 to 0.0082) | >0.2 | −0.0083 (−0.0203 to 0.0037) | 0.172 |
| Time since last menstrual period | −0.0011 (−0.0018 to −0.0005) | 0.001 | −0.0003 (−0.0010 to 0.0004) | >0.2 |
| Weight | 0.0082 (0.0050 to 0.0113) | <0.001 | 0.0090 (0.0046 to 0.0134) | <0.001 |
| Height | 0.0031 (−0.0001 to 0.0063) | 0.057 | −0.0007 (−0.0044 to 0.0031) | >0.2 |
| Wrist size | 0.0088 (−0.0245 to 0.0422) | >0.2 | −0.0267 (−0.0642 to 0.0108) | 0.160 |
| History of fracture | 0.0189 (−0.0287 to 0.0665) | >0.2 | 0.0112 (−0.0088 to 0.0312) | >0.2 |
*
BMD = bone mineral density.
†
History of fracture was recorded as a dichotomized variable, where yes = 1 and no = 0.
‡
In the multivariate analysis, the squared multiple correlation coefficient (R2) was 0.45 for the anterior–posterior spine, 0.25 for the lateral spine, 0.45 for the total hip, 0.45 for the femoral neck, and 0.42 for the trochanter.