Table 2.

Blood chemistries at the end of experiment (12 weeks post nephrectomy)

	Sham	CRF	CRF + HFED
Urea (mg/dl)	54.3 ± 1.8	114.7 ± 4.8**	77.2 ± 14.8#
Scr (mg/dl)	0.5 ± 0.1	1.6 ± 0.5*	1.4 ± 0.3*
Ccr (ml/min/kg BW)	5.7 ± 1.3	1.7 ± 0.4*	1.5 ± 0.4*
Hematocrit (%)	50.2 ± 3.1	38.1 ± 9.6*	45.3 ± 6.3
Blood sugar (mg/dl)	189.3 ± 10.0	179.3 ± 32.6	172.2 ± 24.3
HOMA-IR index	0.42 ± 0.17	2.87 ± 0.92**	1.21 ± 0.39
Plasma albumin (g/l)	27.6 ± 2.1	23.4 ± 2.4**	28.6 ± 1.6##
Tryglycerides (mg/dl)	62.2 ± 48.7	121.8 ± 44.3	176.2 ± 64.4**
Total cholesterol (mg/dl)	71.2 ± 7.7	221.2 ± 20.5***	164.5 ± 45.0***,#
LDL cholesterol (mg/dl)	15.4 ± 8.9	95.9 ± 14.1***	58.6 ± 18.5***,###
HDL cholesterol (mg/dl)	43.3 ± 6.8	100.9 ± 10.4***	70.7 ± 30.7#
HDL/LDL cholesterol	2.75 ± 1.2	1.07 ± 0.2**	1.19 ± 0.2**
Free fatty acids (mg/dl)	0.17 ± 0.1	0.17 ± 0.01	0.40 ± 0.1***,###

Values are given as mean ± SD (n = 6–7)

Scr serum creatinine, Ccr creatinine clearance, HOMA-IR index homeostasis model assessment insulin resistance index

^*p <0.05,

^**p < 0.01,

^***p < 0.001 versus sham groups

^#p < 0.05

^##p < 0.01,

^###p < 0.001 versus CRF groups