. Author manuscript; available in PMC: 2011 Nov 1.

Published in final edited form as: J Nutr Biochem. 2009 Dec 1;21(10):999–1007. doi: 10.1016/j.jnutbio.2009.08.006

Table 3.

Biochemical parameters in CRF rats fed a regular diet or a high-calorie diet

Group	Control	CRF	CRF+high-calorie diet
Total cholesterol (mg/dl)	71.2±9.8	221.2±20.5 ^***	186.4±29.9 ^***
LDL cholesterol (mg/dl)	19.1±6.0	95.9±14.1 ^***	66.7±10.7^***,^#
HDL cholesterol (mg/dl)	45.3±8.6	100.9±10.4 ^***	61.6±19.0^*,^#
Triglycerides (mg/dl)	45.8±18.3	99.7±3.6 ^*	192.8±63.6^***,^#
Free fatty acid (mEq/L)	0.192±0.074	0.220±0.068	0.382±0.052^***,^##
Epididymal fat weight (g)	4.6±0.6	3.6±0.6 ^*	6.2±1.7^*,^##
Abdominal fat weight (g)	2.6±0.7	1.8±0.7	5.6±1.1^***,^###
Urine protein (mg/24 h)	6.7±1.3	80.3±7.3 ^***	31.1±12.8^***,^###
Creatinine clearance (ml/min)	5.62±1.18	1.74±0.38 ^***	1.44±0.33 ^***
Blood urea nitrogen (mg/dl)	25.4±2.1	53.6±5.0 ^***	42.1±9.9^**,^#
Serum creatinine (mg/dl)	0.50±0.1	1.56±0.5 ^***	1.43±0.2 ^***
Systolic blood pressure (mmHg)	123.5±13.4	161.4±10.0 ^**	150.6±14.2 ^**
Diastolic blood pressure (mmHg)	87.5±7.4	117.0±4.5	111.0±13.1
Weight gain (g)	146.0±13.4	119.3±12.0 ^*	148.7±14.6^##
Left kidney weight (g)	1.45±0.16	2.38±0.38 ^***	1.65±0.13^*,^##

Values are given as mean±S.D.

P<.05 versus control groups.

^**

P<.01 versus control groups.

^***

P<.001 versus control groups.

P<.05 versus 5/6 nephrectomized CRF groups.

^##

P<.01 versus 5/6 nephrectomized CRF groups.

^###

P<.001 versus 5/6 nephrectomized CRF groups.