Fig 5. BMC homing into bone marrow.

Donor BMCs from old and young ApoE^−/− mice were treated with PBS (□) or PBS+ CaCl₂ (■), labeled with red fluorescence dye, and injected into irradiated recipient mice. A). Homed BMCs with red fluorescence (arrows pointed) in the bone marrow of the recipient mice were detected under fluorescence microscopy. B). Homed cells were quantified from the sections of recovered bones by counting fluorescent cells under microscope. N=4, * p<0.05. C). Concentrations of SDF-1α in serum and bone marrow from old and young ApoE^−/− mice were measured by ELISA (n= 3; **p<0.01).