Fig. 1.

(A–C) Immunohistochemical analysis of LOX-1 expression, 1 week following gene transfer. (A) Anti-LOX-1 antibody; (B) nonimmune goat control; (C) anti-LOX-1 antibody on RAd66 control transduced artery. Intense staining of luminal cells was observed, which by position and shape were predominantly identified as endothelial cells. (D–F) Representative longitudinal sections of transduced arteries 6 weeks post gene transfer. (D) Vehicle control treated; (E) RAd66 control virus transduced; (F) AdLOX-1-transduced artery.