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. Author manuscript; available in PMC: 2011 Nov 2.
Published in final edited form as: J Biol Chem. 2003 May 13;278(30):27540–27547. doi: 10.1074/jbc.M301763200

Fig. 11. DMS inhibits HL60 SOCE initiated by direct store depletion.

Fig. 11

HL60 (upperpanel) and HL60-PMN (lowerpanel) cells were studied in a like manner to the PMN studied in Fig. 10. Quantitative Ca2+ store release was unaffected by the differentiation of the cells (note the difference in scale) or by the presence of DMS. Again though, 10 μm DMS was found to inhibit TG-initiated SOCE to the level of “leak.” SOCE response to TG (which is GPCR-independent) was markedly increased by differentiation of the cells.