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. Author manuscript; available in PMC: 2011 Nov 2.
Published in final edited form as: Nature. 2010 Jun 24;465(7301):1033–1038. doi: 10.1038/nature09144

Figure 3. Loss of PTENP1 in cancer.

Figure 3

a–b. Expression level of PTEN (black) and PTENP1 (red) in a panel of normal human tissues (a) and prostate tumour samples (b). Linear regression of PTEN vs PTENP1 expression is shown in the upper left corner. c. Cluster analysis of 48 sporadic colon cancer samples interrogated by Affymetrix Human SNP Array. d. Heat map and Cluster analysis of Affymetrix Human Exon 1.0 ST Array for normalized PTEN intensity values. e. Plot of log-ratio of PTENP1 copy number (CN) against log10 PTEN expression intensity. Lines of best fit represent regression analyses of two populations. The correlation coefficient (r) measures the reliability and the p-value measures the statistical significance of the correlation between the x and y.