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. Author manuscript; available in PMC: 2012 Mar 8.
Published in final edited form as: N Engl J Med. 2011 Sep 8;365(10):901–908. doi: 10.1056/NEJMoa1104119

Table 2.

Body-Mass Index (BMI) and Waist Circumference in Relation to Death from Specific Causes among Women Who Never Smoked.*

Variable Death from Cardiovascular Disease Death from Cancer Death from Other Causes
No. of Deaths Hazard Ratio (95% CI) No. of Deaths Hazard Ratio (95% CI) No. of Deaths Hazard Ratio (95% CI)
Adjusted Additionally Adjusted for BMI Adjusted Additionally Adjusted for BMI Adjusted Additionally Adjusted for BMI
BMI

 20.0–24.9 21 1.00 (reference) 71 1.00 (reference) 64 1.00 (reference)

 25.0–29.9 62 2.25 (1.36–3.72) 106 1.14 (0.84–1.54) 80 1.00 (0.72–1.40)

 30.0–34.9 42 2.77 (1.62–4.73) 52 1.03 (0.71–1.48) 53 1.16 (0.80–1.68)

 35.0–49.9 45 3.90 (2.29–6.64) 45 1.23 (0.84–1.81) 65 1.76 (1.23–2.52)

 P value for trend <0.001 0.42 <0.001

Waist circumference

 26–29 in. 14 1.00 (reference) 1.00 (reference) 56 1.00 (reference) 1.00 (reference) 48 1.00 (reference) 1.00 (reference)

 30–33 in. 34 1.97 (1.05–3.69) 1.51 (0.78–2.92) 76 1.08 (0.76–1.53) 1.05 (0.72–1.52) 57 0.97 (0.66–1.44) 0.98 (0.65–1.48)

 34–37 in. 44 3.37 (1.83–6.22) 2.18 (1.10–4.34) 69 1.28 (0.89–1.85) 1.21 (0.80–1.85) 52 1.08 (0.72–1.62) 1.07 (0.66–1.72)

 38–47 in. 41 4.29 (2.30–8.01) 2.29 (1.08–4.85) 36 0.94 (0.61–1.45) 0.82 (0.48–1.39) 54 1.48 (0.99–2.21) 1.34 (0.79–2.29)

 P value for trend <0.001 0.03 0.93 0.61 0.04 0.24
*

The BMI is the weight in kilograms divided by the square of the height in meters. To convert inches to centimeters, multiply by 2.54.

Hazard ratios were adjusted for age, questionnaire cycle, education, marital status, vigorous physical activity, and alcohol intake. Hazard ratios for waist circumference were additionally adjusted for BMI.