Comparison of projected rates of influenza-related deaths and years of life lost (YLL) for 3 pandemic scenarios. Solid lines show YLL, and dashed lines show deaths (both per 100,000 population). Estimates are based on historical age-specific influenza-related mortality rates from the 1918 pandemic (A), the 1957 pandemic (B), and the 1968 pandemic (C), projected onto the 2000 US population structure and life expectancies. The age groups studied vary between the pandemics due to the availability of historical data [11, 23, 25].