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. 2011 Oct 31;195(3):417–433. doi: 10.1083/jcb.201103097

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© 2011 Kim et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 9. — Cluster analysis of neuroblastoma clinical cohort. (A) miR-34a expression levels in 1p36-positive and 1p36-deleted human neuroblastoma cells. (B) Snail1 and Slug/Snail2 protein levels in 1p36-positive and 1p36-deleted neuroblastoma cells as determined by Western blot analysis. Cell lines expressing recombinant Snail1 or recombinant Slug/Snail2 were used as positive controls. (C) Heat map shows average-linkage hierarchical clustering, using a Euclidean distance metric, performed on 23 neuroblastoma patient samples. Clinical samples harboring a deletion of chromosome 1p are indicated with a red bar. Two distinct clusters, A and B, are highlighted in the gray boxes.