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Effect of different concentrations of n-frutalin and r-frutalin on HeLa cells proliferation at 24 and 48 h. Each time point is shown as mean ± SEM of at least 3 replicates (n = 3); *P < 0.05. No statistically significant differences were observed in terms of toxicity between the same concentrations of recombinant and native frutalin, regardless of concentration and time point analysed.
