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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Biomed Mater. 2011 Mar 24;6(2):025011. doi: 10.1088/1748-6041/6/2/025011

Figure 8.

Figure 8

Expression of the tenomodulin gene in response to treatment with GDF-5. (A) Cells on 3D scaffold, and (B) on 2D film. Gene expression for tenomodulin, a marker of the mature tendon phenotype, was not significantly different in cells treated with GDF-5 compared to cells cultured in basal medium without GDF-5 at early and late time points. Tenomodulin gene expression by cells on 3D scaffold increased over time (A), and was higher than expression by cells on 2D film (B) at 7 days. Gene expression data is normalized to the 18s gene and expression of day 3 on 3D scaffold without GDF-5 (0ng/mL).