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Proposed mechanisms of action of ribavirin. IMPDH, inosine monophosphate dehydrogenase; TH, T helper cell. TNF, tumor necrosis factor. (Reprinted with permission from J.J. Feld and J.H. Hoofnagle. Mechanism of action of interferon and ribavirin in treatment of hepatitis C Jordan J. Nature 2005, 436:967-972.)
